Leukoplakia is most accurately described as which of the following?

• A. A white patch on the mucosa that can be scraped off
• B. A white lesion that cannot be scraped off
• C. A red patch on the mucosa
• D. A yellow plaque on the tongue

Answer: (B)

Leukoplakia is described as a white patch or plaque on the oral mucosa that cannot be rubbed or scraped off with a gauze or finger. This quality—being fixed and not wipeable—helps distinguish it from other white oral lesions, such as candidal patches, which can usually be wiped away to reveal a red or inflamed surface underneath. Leukoplakia is considered a potentially malignant condition, so any non-scrapable white patch warrants professional assessment to rule out dysplasia or cancer, often involving biopsy if indicated. It tends to be associated with risk factors like tobacco use and alcohol intake and can occur anywhere in the mouth, though it’s commonly seen on the cheek mucosa or tongue. In practice, note the patch’s size, border, texture, and exact location, educate the patient about quitting irritants, and arrange appropriate referral and follow-up rather than making a diagnosis yourself.